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Hydrogen peroxide H O is shown to readily promote EADs
2019-06-20
Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis
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Any abnormality causing a loss of
2019-06-20
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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En el Estudio preliminar el lector
2019-06-20
En el “Estudio preliminar”, el lector encontrará un magnífico marco de referencia para ubicar con precisión la obra. Contra una vieja mala costumbre de la crítica mexicañista más convencional de repetir una y otra vez los juicios críticos de los grandes maestros, Belem Clark de Lara teje una trama m
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Several mechanisms have been proposed Due to a greater
2019-06-20
Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the
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br The Editorial in about global
2019-06-19
The Editorial in about global health inequity raises some important issues. The global health order Amikacin long ago acknowledged the worldwide disparities in health, but it has failed to take action; most of the efforts have been made in reporting the disparities among specific population grou
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In the wake of these commitments comes a
2019-06-19
In the wake of these commitments comes a reminder of the enormity of the task at hand. In , Alexandre Delamou and colleagues present data on the lasting effect of the Ebola virus disease epidemic on maternal and child health-care services in the rural Forest region of Guinea—the location of approxim
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Introduction Bone metastases are a common
2019-06-19
Introduction Bone metastases are a common manifestation of cancer [1]. Most patients present with pain and impaired mobility, while others can develop complications such as pathological fractures and na inhibitor of the spinal cord or cauda equina [2]. Many randomized studies have been conducted t
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Human ether a go go related
2019-06-19
Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium APETx2 Supplier that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated
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Aunque m s por afinidad electiva que por propia
2019-06-19
Aunque más por afinidad electiva que por propia decisión del autor, lo cierto es que justamente ese conjunto de rasgos aproximaría la obra al llamado libro de artista, modalidad creativa tan característicamente vanguardista como la simulación crítica, la interdisciplinariedad, el collage, el disposi
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br Deseo y nostalgia el
2019-06-19
Deseo y nostalgia: el discurso de lo real en la Historia verdadera Más allá de las afirmaciones de verdad y realidad en las que el texto incurre a cada paso; más allá del detalle (en sus usos narratológicos, retóricos y polémicos); más allá de cierta mimesis entendida como artificio y concebida t
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br Transici n y representaci n
2019-06-19
Transición y representación ¿Qué pasó con esa idea del campesino nacional, anacrónico y en conflicto con la modernidad en el momento posrevolucionario? Su reinscripción como una idealización coincide con los pactos de transición de régimen. A la vez, la participación militar de los campesinos com
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Sin embargo m s all de las coincidencias sobre qu
2019-06-19
Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio
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En una clara cr tica al
2019-06-19
En una clara crítica al modelo neoliberal gay importado de Estados Unidos, Néstor Perlongher sostiene que “el gay pasa ω-Agatoxin TK tomarse como modelo de conducta. Este operativo de normalización arroja a los bordes a los nuevos marginados, los excluidos de la fiesta: travestis, locas, chongos, gr
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br Introduction Multiple signal transduction
2019-06-19
Introduction Multiple signal transduction pathways in normal and malignant LLY507 converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (MOMP),
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In recent years there has been
2019-06-19
In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mRN
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