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The BDNF Val Met polymorphism is also
2021-04-09
The BDNF Val66Met polymorphism is also associated with decreased dendritic arborization and impaired long-term potentiation [25]. This is particularly important for the hippocampus, and healthy individuals with a BDNF Val66Met allele have decreased hippocampal volumes [30]. Hippocampal atrophy is co
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Introduction Prolyl hydroxylation is a widely observed
2021-04-09
Introduction Prolyl hydroxylation is a widely observed post translational modification in collagen, an abundant animal protein. The high content (~13% per chain of the triple helical structure) of 4-hydroxyproline (Hyp,O) in collagen, togather with the natural abundance of collagen has led to the e
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br Disclosures br Introduction The presence of anti
2021-04-09
Disclosures Introduction The presence of anti-viral T-cell immunity is crucial for effective and sustained protection against Cytomegalovirus (CMV) following allogeneic stem cell transplantation (alloSCT) [1]. In vitro and in vivo T-cell depletion (TCD) via addition of the anti-CD52 monoclonal
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All of the studies referred to above were on microvillous
2021-04-09
All of the studies referred to above were on microvillous membrane from hSTB; however, there is little information regarding conductances in the basal membrane. Illsley and Sellers, using a fluorescent technique, determined the relative permeabilities of cations and chloride in basal membrane vesicl
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melk pathway Research done thus far supports the hypothesis
2021-04-09
Research done thus far supports the hypothesis that MPA has detrimental effects on cognition, alone and in combination with estrogen; there are other FDA-approved progestogens that satisfy the uterus opposing effects that have not been cognitively profiled. An important goal to aid women's health is
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Elastase belongs to chymotrypsin family of
2021-04-09
Elastase belongs to chymotrypsin family of proteases and it is responsible for the breakdown of elastin and other proteins, such as collagen and fibronectin, which are fundamental for the ECM elastic properties (Imokawa and Ishida, 2015). Misregulations of this enzyme are involved in skin ageing pro
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Tumor associated macrophages TAMs one of the limiting factor
2021-04-08
Tumor-associated macrophages (TAMs)—one of the limiting factors in anti-tumor immunity—are associated with the poor clinical outcome in most carcinomas, owing to their potential to promote angiogenesis and local invasion, increase the metastasis of tumor cells, and inhibit the anti-tumor immunity.11
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br Proposed methodology At the outset
2021-04-08
Proposed methodology At the outset, the wind power outputs must be obtained which are to be included in the OPF model. This work utilizes a modified version of the simulation method. Rather than using the simulated wind power values for each hour of the year, the probability of each wind power in
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Cyclophosphamide Phytophthora capsici is a phytopathogenic o
2021-04-08
Phytophthora capsici is a phytopathogenic oomycete, a lineage of eukaryotic microorganisms in the kingdom Stramenopila, which causes devastating diseases on many economically important vegetables [15]. Hyps are present in the Phytophthora cell wall proteins [16] and phytotoxic elicitor proteins [17]
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In this study we also conducted an analysis
2021-04-08
In this study, we also conducted an analysis comparing the expression profiling of Hh genes among the sarcomas investigated. In these tumors, the IHH gene showed a higher expression level than PTCH1 gene in RMS and SS samples (pegfr inhibitors in human RMS cell lines as well as mouse NIH-3T3 fibrob
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It has been reported that Eph Ephrin are
2021-04-08
It has been reported that Eph/Ephrin are involved in the regulation of the tumor angiogenesis [10], [11], [12]. The distinct and specific involvement of cp-690550 and veins in tumor angiogenesis is unclear. EphrinB2 is expressed in arteries and its receptor EphB4 is expressed in veins; these molecu
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ampar br Thy nephritis is one
2021-04-08
Thy1.1 nephritis is one of the most commonly used models to study the course of immunoglobulin A and other mesangioproliferative nephropathies. To date, most of the studies have focused on mesangial and, to a lesser extent, endothelial cell recovery following capillary damage, whereas data concern
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In the present study it was particularly of interest that
2021-04-08
In the present study, it was particularly of interest that intravesical administration of PGE2 evoked ONO-8130-reversible rapid phosphorylation of ERK in the L6 spinal cord. Detection of phosphorylated ERK is now often used as a marker for somatic and visceral nociception, including AMG 487 pain [8
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The preceding results show no association between the EP
2021-04-08
The preceding results show no association between the EP1 gene polymorphisms and suicide completers in the Japanese population. Impulsive aggression is one of the most important risk factors for suicide especially in the younger generation (Brent et al., 2002, Melhem et al., 2007). EP1 knockout mice
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br Methods br Results br Discussion I R induces
2021-04-08
Methods Results Discussion I/R induces oxidative stress and increases the intracellular levels of ROS, resulting in tissue damage [31]. ROS is generated by mitochondrial electron transport chain, nicotinamide Mdivi 1 dinucleotide phosphate (NADPH) oxidase complex, xanthine oxidase and NOS
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