• Subsequently more detailed mapping was performed

  2019-04-26

  

  Subsequently, more detailed mapping was performed to identify the Purkinje potential preceding the QRS onset of the PVCs in their region of origin (Fig. 2B). Radiofrequency ablation was performed at the site of the earliest Purkinje potential preceding the local ventricular potential (Fig. 2C and D)

• br Genetic basis Similar to other arrhythmia syndromes Bruga

  2019-04-26

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• Class IC antiarrhythmic drugs such as pilsicainide

  2019-04-26

  

  Class IC antiarrhythmic drugs such as pilsicainide and propafenone have been used to terminate or prevent ATs, particularly atrial fibrillation [15–17]. Pilsicainide and propafenone in Japan, and ajmaline in Europe, are commonly used as first-line drugs for antiarrhythmic therapy [13]. We often enco

• br Methods The study protocol was approved by the

  2019-04-26

  

  Methods The study protocol was approved by the ethics committee at Juntendo University Nerima Hospital. After informed consent was obtained, SBC measurement was performed using a blood sample from each participant. Plasma was separated from each sample immediately after collection by centrifugati

• Common and rare SCN A variants may contribute

  2019-04-26

  

  Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

• Introduction Multiple myeloma MM is the most

  2019-04-25

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• Interim measures however are not nearly enough

  2019-04-25

  

  Interim measures, however, are not nearly enough. A massive expansion of the blood donor pool is needed, but scaling up blood donation in the low-resource world is no easy task. WHO has long advocated a set of interventions to fortify a nation\'s blood supply, but countries will have difficulty solv

• Despu s de mucho tiempo Argentina dio una

  2019-04-25

  

  Después de mucho tiempo, Argentina dio una respuesta positiva a la decisión política, tanto de Colombia como de Perú, de reactivar las relaciones bilaterales. En cambio, en el nexo con Chile, Argentina no tenía que dar respuestas sino buscar alternativas para tratar de salir del progresivo debilitam

• Currently we are unable to fully understand the diversity

  2019-04-25

  

  Currently, we are unable to fully understand the entacapone and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the prese

• Introduction Lung cancer is the most

  2019-04-25

  

  Introduction Lung cancer is the most common and deadly malignancy in Taiwan, the cause of an estimated 33,919 new cases between 2002 and 2008. Although the 5-year survival rate is only 15.9%, the overall survival rate is as high as 60.7% in patients whose tumors are confined to the primary site at

• br Homing of DTCs to the HSC niche The HSC

  2019-04-25

  

  Homing of DTCs to the HSC niche The HSC niche is a complex microenvironment comprised of many cell types, including endothelial cells, adipocytes, osteoclasts, osteomacs, and tsa trichostatin of osteoblastic lineage [5]. A healthy HSC niche provides homing signals to healthy HSCs in order to pro

• Most forms of AVNRT are created by

  2019-04-25

  

  Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer

• The gallstone Lith gene map has been

  2019-04-25

  

  The gallstone (Lith) gene map has been updated, which lists all known genetic loci that confer gallstone susceptibility, as well as candidate genes in inbred strains of mice. Understanding molecular genetics of gallstone disease in mice will push for the identification of human Lith genes. In additi

• Interim measures however are not nearly enough

  2019-04-25

  

  Interim measures, however, are not nearly enough. A massive expansion of the blood donor pool is needed, but scaling up blood donation in the low-resource world is no easy task. WHO has long advocated a set of interventions to fortify a nation\'s blood supply, but countries will have difficulty solv

• Al ser verdad lo anterior no lo es

  2019-04-25

  

  Al ser verdad lo anterior, no lo es menos que la cultura asentada en tiempos coloniales, a diferencia de la que llegó en los primeros tiempos de la conquista, respondía a la relativa ignorancia del mundo clásico en España, sobre todo del griego. Fue el país donde más se leyeron sus autores en traduc

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